Part 2 Cystic Fibrosis Activity Genetics Worksheet printable pdf download

Part 2 Cystic Fibrosis Activity Genetics Worksheet

Cystic F ibrosis A ctivity

Part 2

Scenario: You sent DNA samples to a genetics lab for sequencing. The lab has sent you

the D NA s equence f or a s mall p ortion o f t he c ftr g ene f rom e ach p atient.

Remember h ow p roteins a re m ade?

DNA

RNA

Protein

You n ow h ave t o t ake t he s equences y ou o btained f rom t he l ab a nd c onvert t hem i nto a

protein sequence. You will then be able to compare your patients’ CFTR protein to a

normal C FTR p rotein t o m ake t he f inal d iagnosis o f C ystic F ibrosis.

Instructions:

1.) First, you must transcribe the DNA sequences below to RNA sequences, and write

them i n t he s paces p rovided.

DNA

RNA

Patient _ __ c ftr D NA s equence:

T T A

T A G

A A A

C C A

C A A

_ _ _ _ _ _

RNA:

_ _ _

Patient _ __ c ftr D NA s equence:

T T A

T A G

T A A

A G A

C C A

C A A

_ _ _ _ _ _

RNA:

_ _ _

2.) Now that you have transcribed the DNA sequence into an RNA sequence, you need

to t ranslate t he R NA s equence i nto a p rotein s equence. C opy y our R NA s equences o n t o

the n ext p age i n t he s pace p rovided.

Part 2 Cystic Fibrosis Activity Genetics Worksheet